Django is an extremely popular and fully featured server-side web framework, written in Python. In other words, it is a full-stack and an open-source Python web development framework. Django mainly comes equipped with ready-to-use libraries. Some of its outstanding features are URL routing, template engine, authentication, database schema migrations, and an object-relational mapper (ORM). Altogether, these make this framework highly fast, scalable, and versatile. Moreover, Django is quite compatible with a host of databases including MySQL, SQLite, PostgreSQL, and Oracle. It uses ORM to map objects to database tables. Nevertheless, this framework enables you to develop any type of application that you wish for, from small to large web applications.

Pyramid is another open-source framework. This Python web development framework works on Python 3 & strives to achieve as much as possible with minimum complexity. The best part about this framework is that it can run on both small & large applications. Some of the highlights of the Pyramid framework includes adaptable validation and approval, templating and resource details, and single-document application. Pyramid framework provides truly dependable safety efforts and screen across control records. Moreover, it is also commendable for mapping URLs to code. However, if one wants to build a highly secure and robust web application, then all he needs is to hire a Python developer.

Web2Py is an open-source full-stack development framework which allows the client to design things quite easily and rapidly. It also helps in supporting all well-known working frameworks. Web2Py basically helps in rearranging the web application development process with the help of SQL database, web server, and an online interface. However, this framework also allows users to alter, construct as well as oversee web applications with the help of internet browsers. One of the essential features of this framework is that it employs the ticket allowing the instrument to follow the status and blunders. It has in-fabricated segments to manage responses, sessions, HTTP demands, and treats.

TurboGears, born as a full-stack layer on top of Pylons, is now a standalone WSGI web framework that can act both as a full-stack framework (like Django) or as a micro framework (like Flask). Originally inspired by RubyOnRails it’s based on MVC where the controller dispatches the request to a set of actions exposed from the controller itself. TurboGears, in its full-stack mode, provides all the features you would require during the development of a web application: Identification and Authentication; Authorization; Autogenerated Admin and CRUD; Sessions; Caching; Schema Migrations; Master/Slave Database Queries Balancing; Request Bound Transactions; Interactive Debugger; Builtin Profiling; and Pluggable Applications.

CubicWeb is a semantic web application framework, licensed under the LGPL, that empowers developers to efficiently build web applications by reusing components (called cubes) and following the well-known object-oriented design principles. Its main features are: an engine driven by the explicit data model of the application; a query language named RQL similar to W3C’s SPARQL; a selection+view mechanism for semi-automatic XHTML/XML/JSON/text generation; a library of reusable components (data model and views) that fulfill common needs; the power and flexibility of the Python programming language; and the reliability of SQL databases, LDAP directories, Subversion and Mercurial for storage backends.